Common Name: 4-Dimethylaminoazobenzene CAS Number: 60-11-7 DOT Number: None Date: October 30, 1986 ----------------------------------------- HAZARD SUMMARY * 4-Dimethylaminoazobenzene can affect you when breathed in and by passing through your skin. * 4-Dimethylaminoazobenzene is a CARCINOGEN HANDLE WITH EXTREME CAUTION. * This chemical may damage the developing fetus. * Exposure may irritate the skin. Repeated exposure can cause a skin rash. IDENTIFICATION 4-Dimethylaminoazobenzene is a yellow, crystal (sand or sugar like) solid. It may also exist in a solution. It is used in chemical analysis. REASON FOR CITATION * 4-Dimethylaminoazobenzene is on the RTK Hazardous Substance List because it is regulated by OSHA and cited by NTP and CAG. * This chemical is also on the Special Health Hazard Substance List because it is a CANCER CAUSING AGENT and a MUTAGEN. * Definitions are attached. HOW TO DETERMINE IF YOU ARE BEING EXPOSED * Exposure to hazardous substances should be routinely evaluated. This may include collecting personal and area air samples. You can obtain copies of sampling results from your employer. You have a legal right to this information under OSHA 1910.20. * If you think you are experiencing any work related health problems, see a doctor trained to recognize occupational diseases. Take this Fact Sheet with you. WORKPLACE EXPOSURE LIMITS * No exposure limits have been set. A full OSHA standard, 1910.1015, has been established for this substance. * 4-Dimethylaminoazobenzene is a PROBABLE CANCER CAUSING AGENT in humans. There may be no safe level of exposure to a carcinogen, so all contact should be reduced to the lowest possible level. WAYS OF REDUCING EXPOSURE * Where possible, enclose operations and use local exhaust ventilation at the site of chemical release. If local exhaust ventilation or enclosure is not used, respirators should be worn. * Establish a regulated area where 4-Dimethylaminoazobenzene is manufactured, used or stored as required in the OSHA standard 1910.1015. * Wear protective work clothing. * Wash thoroughly immediately after exposure to 4- Dimethylaminoazobenzene and on each exit from a regulated area. * Post hazard and warning information in the work area. In addition, as part of an ongoing education and training effort, communicate all information on the health and safety hazards of 4-Dimethylaminoazobenzene to potentially exposed workers. This Fact Sheet is a summary source of information of all potential and most severe health hazards that may result from exposure. Duration of exposure, concentration of the substance and other factors will affect your susceptibility to any of the potential effects described below. ------------------------------------------ HEALTH HAZARD INFORMATION Acute Health Effects The following acute (short term) health effects may occur immediately or shortly after exposure to 4-Dimethylaminoazobenzene: * The solid or solutions of this chemical may irritate the skin, causing a rash or burning feeling on contact. Chronic Health Effects The following chronic (long term) health effects can occur at some time after exposure to 4-Dimethylaminoazobenzene and can last for months or years: Cancer Hazard * 4-Dimethylaminoazobenzene is a PROBABLE CANCER CAUSING AGENT in humans. It has been shown to cause liver, bladder, lung, and skin cancer in animals. * Many scientists believe there is no safe level of exposure to a cancer causing agent. Such substances may also have the potential for causing reproductive damage in humans. Reproductive Hazard * 4-Dimethylaminoazobenzene may damage the developing fetus. Other Long Term Effects * Repeated exposure may cause a skin rash. MEDICAL Medical Testing There is no special test for this chemical. However, if illness occurs or over exposure is suspected, medical attention is recommended. Any evaluation should include a careful history of past and present symptoms with an exam. Medical tests that look for damage already done are not a substitute for controlling exposure. Any evaluation should include a careful history of past and present symptoms with an exam. Medical tests that look for damage already done are not a substitute for controlling exposure. Request copies of your medical testing. You have a legal right to this information under OSHA 1910.20. WORKPLACE CONTROLS AND PRACTICES Unless a less toxic chemical can be substituted for a hazardous substance, ENGINEERING CONTROLS are the most effective way of reducing exposure. The best protection is to enclose operations and/or provide local exhaust ventilation at the site of chemical release. Isolating operations can also reduce exposure. Using respirators or protective equipment is less effective than the controls mentioned above, but is sometimes necessary. In evaluating the controls present in your workplace, consider: (1) how hazardous the substance is, (2) how much of the substance is released into the workplace and (3) whether harmful skin or eye contact could occur. Special controls should be in place for highly toxic chemicals or when significant skin, eye, or breathing exposures are possible. In addition, the following controls are recommended: * Establish a regulated area where 4-Dimethylaminoazobenzene is manufactured, used, or stored. * Where possible, automatically pump liquid 4- Dimethylaminoazobenzene from containers to process containers. * Specific engineering controls are required for this chemical by OSHA. Refer to the OSHA standard 1910.1015 on 4- Dimethylaminoazobenzene. Good WORK PRACTICES can help to reduce hazardous exposures. The following work practices are recommended: * Workers whose clothing has been contaminated by 4- Dimethylaminoazobenzene should change into clean clothing promptly. * Do not take contaminated work clothes home. Family members could be exposed. * Contaminated work clothes should be laundered by individuals who have been informed of the hazards of exposure to 4- Dimethylaminoazobenzene. * On skin contact with 4-Dimethylaminoazobenzene, immediately wash or shower to remove the chemical. * Wash any areas of the body that may have contacted 4- Dimethylaminoazobenzene at the end of each workday, whether or not known skin contact has occurred. * Do not eat, smoke, or drink where 4-Dimethylaminoazobenzene is handled, processed, or stored, since the chemical can be swallowed. Wash hands carefully before eating or smoking. PERSONAL PROTECTIVE EQUIPMENT WORKPLACE CONTROLS ARE BETTER THAN PERSONAL PROTECTIVE EQUIPMENT. However, for some jobs (such as outside work, confined space entry, jobs done only once in a while, or jobs done while workplace controls are being installed), personal protective equipment may be appropriate. The following recommendations are only guidelines and may not apply to every situation. Clothing * Avoid skin contact with 4-Dimethylaminoazobenzene. Wear protective gloves and clothing. Safety equipment suppliers/manufacturers can provide recommendations on the most protective glove/ clothing material for your operation. * All protective clothing (suits, gloves, footwear, headgear) should be clean, available each day, and put on before work. Eye Protection * Eye protection is included with the recommended respiratory protection. Respiratory Protection IMPROPER USE OF RESPIRATORS IS DANGEROUS. Such equipment should only be used if the employer has a written program that takes into account workplace conditions, requirements for worker training, respirator fit testing and medical exams, as described in OSHA 1910.134. * At any exposure level, use a MSHA/NIOSH approved supplied air respirator with a full facepiece operated in the positive pressure mode or with a full facepiece, hood, or helmet operated in the continuous flow mode. An MSHA/NIOSH approved self contained breathing apparatus with a full facepiece operated in pressure demand or other positive pressure mode is also recommended. Common Name:4-Dimethylaminoazobenzene DOT Number: None DOT Emergency Guide code: No Citation CAS Number: 60-11-7 ---------------------------------------- NJ DOH Hazard rating FLAMMABILITY Not Found REACTIVITY Not Found ---------------------------------------- CANCER CAUSING AGENT DOES NOT BURN ---------------------------------------- Hazard Rating Key: 0=minimal; 1=slight; 2=moderate; 3=serious; 4=severe FIRE HAZARDS * 4-Dimethylaminoazobenzene is a non combustible solid. * Extinguish fire using an agent suitable for type of surrounding fire. 4-Dimethylaminoazobenzene itself does not burn. * If employees are expected to fight fires, they must be trained and equipped as stated in OSHA 1910.156. SPILLS AND EMERGENCIES If 4-Dimethylaminoazobenzene is spilled, take the following steps: * Restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. * Ventilate the area of spill or leak. * Collect spilled material in the most convenient and safe manner and deposit in sealed containers for reclamation or for disposal in an approved facility. Liquid containing 4- Dimethylaminoazobenzene should be absorbed in vermiculite, dry sand, earth or a similar material. * It may be necessary to contain and dispose of 4- Dimethylaminoazobenzene as a HAZARDOUS WASTE. Contact your Environmental Program for specific recommendations. ========================================== FOR LARGE SPILLS AND FIRES immediately call your fire department. ========================================== HANDLING AND STORAGE * Prior to working with 4-Dimethylaminoazobenzene you should be trained on its proper handling and storage. * 4-Dimethylaminoazobenzene must be used, handled, and stored in compliance to the OSHA standard 1910.1015. FIRST AID POISON INFORMATION Eye Contact * Immediately flush with large amounts of water for at least 15 minutes, occasionally lifting upper and lower lids. Skin Contact * Quickly remove contaminated clothing. Immediately wash area with large amounts of soap and water. PHYSICAL DATA Water Solubility: Insoluble OTHER COMMONLY USED NAMES Chemical Name: Benzeneamine, N,N Dimethyl 4-(Phenylazo) Other Names and Formulations: Butter yellow; Methyl yellow; DAB. ------------------------------------------ Not intended to be copied and sold for commercial purposes. ------------------------------------------ NEW JERSEY DEPARTMENT OF HEALTH Right to Know Program CN 368, Trenton, NJ 08625 0368 ------------------------------------------ ------------------------------------------ ECOLOGICAL INFORMATION 4-Dimethylaminoazobenzene is a yellow, crystalline solid used for the determination of free hydrochloric acid in gastric juice, in spot test identification of peroxidized fats, and as an indicator of pH. It may enter the environment from industrial or municipal discharges, or spills. ACUTE (SHORT-TERM) ECOLOGICAL EFFECTS Acute toxic effects may include the death of animals, birds, or fish, and death or low growth rate in plants. Acute effects are seen two to four days after animals or plants come in contact with a toxic chemical substance. 4-Dimethylaminoazobenzene has moderate acute toxicity to aquatic life. Insufficient data are available to evaluate or predict the short-term effects of 4-Dimethylaminoazobenzene to plants, birds, or land animals. CHRONIC (LONG-TERM) ECOLOGICAL EFFECTS Chronic toxic effects may include shortened lifespan, reproductive problems, lower fertility, and changes in appearance or behavior. Chronic effects can be seen long after first exposure(s) to a toxic chemical. 4-Dimethylaminoazobenzene has moderate chronic toxicity to aquatic life. Insufficient data are available to evaluate or predict the long-term effects of 4-Dimethylaminoazobenzene to plants, birds, or land animals. WATER SOLUBILITY 4-Dimethylaminoazobenzene is moderately soluble in water. Concentrations of between 1 to 1,000 milligrams will mix with a liter of water. DISTRIBUTION AND PERSISTENCE IN THE ENVIRONMENT 4-Dimethylaminoazobenzene is moderately persistent in water, with a half-life of between 20 to 200 days. The half-life of a pollutant is the amount of time it takes for one-half of the chemical to be degraded. About 37% of this chemical will eventually end up in water; about 32.5% will end up in terrestrial soils; about 30.3% will end up in aquatic sediments; and the rest will end up in the air. BIOACCUMULATION IN AQUATIC ORGANISMS Some substances increase in concentration, or bioaccumulate, in living organisms as they breathe contaminated air, drink contaminated water, or eat contaminated food. These chemicals can become concentrated in the tissues and internal organs of animals and humans. The concentration of 4-Dimethylaminoazobenzene found in fish tissues is expected to be somewhat higher than the average concentration of 4-Dimethylaminoazobenzene in the water from which the fish was taken. SUPPORT DOCUMENT: AQUIRE Database, ERL-Duluth, U.S. EPA.